Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847089 | 0.88 | POLB (0.33) | TLR7NPC1RAB9ADDR1GRIN1 | |
| SCHEMBL7849498 | 0.85 | TLR7 (0.33) | TLR7P2RX3MEN1KMT2ANPSR1 | |
| SCHEMBL6087138 | 0.84 | DRD1 (0.36) | TLR7MEN1KMT2AHTTRECQL | |
| SCHEMBL8189652 | 0.83 | KDM4E (0.45) | TLR7P2RX3MEN1KMT2AHTT | |
| SCHEMBL7848188 | 0.80 | TLR7 (0.33) | TLR7NPC1RAB9ADDR1GRIN1 | |
| SCHEMBL7847258 | 0.79 | ALDH1A1 (0.34) | RAB9AP2RX3DDR1GRIN1GRIN2B | |
| SCHEMBL7847583 | 0.79 | TLR7 (0.32) | TLR7NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7836586 | 0.78 | HSD17B10 (0.51) | GRIN1GRIN2BMEN1KMT2AMAPT | |
| SCHEMBL7847304 | 0.78 | GRIN1 (0.44) | GRIN1GRIN2BMEN1KMT2ANOX4 | |
| SCHEMBL7848837 | 0.76 | TP53 (0.39) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |