Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 8/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849648 | 0.86 | GRIN1 (0.36) | GRIN1GRIN2BKMT2ASMN1; SMN2 | |
| SCHEMBL7848879 | 0.84 | TYMS (0.35) | DDR1 | |
| SCHEMBL7843371 | 0.84 | ALDH1A1 (0.41) | MAPTTSHRCYP3A4MEN1KMT2A | |
| SCHEMBL6085665 | 0.83 | TSHR (0.34) | GRIN1GRIN2BMAPTTSHRNR3C1 | |
| SCHEMBL7845270 | 0.82 | MTNR1A (0.38) | GRIN1GRIN2BMAPTMEN1KMT2A | |
| SCHEMBL7837651 | 0.78 | MTNR1A (0.50) | GRIN1GRIN2BMAPTTSHRCYP3A4 | |
| SCHEMBL7848132 | 0.77 | GRIN1 (0.40) | GRIN1GRIN2BNR3C1KMT2A | |
| SCHEMBL9009378 | 0.76 | NOTUM (0.30) | — | |
| SCHEMBL7848982 | 0.75 | GRIN1 (0.42) | GRIN1GRIN2BTSHRCYP3A4MEN1 | |
| SCHEMBL7845199 | 0.74 | GRIN1 (0.45) | GRIN1GRIN2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |