Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18740602 | 0.89 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18740533 | 0.88 | HTT (0.41) | RIPK1 | |
| SCHEMBL17224584 | 0.82 | KMT2A (0.55) | KMT2ADRD2 | |
| SCHEMBL17224647 | 0.77 | GAA (0.32) | RIPK1 | |
| SCHEMBL7846754 | 0.74 | ALDH1A1 (0.42) | KMT2ADRD4DRD2DRD3SMN1; SMN2 | |
| SCHEMBL18763395 | 0.74 | GAA (0.43) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL18763261 | 0.72 | KMT2A (0.40) | KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL2033656 | 0.72 | RIPK1 (0.45) | RIPK1 | |
| SCHEMBL18763112 | 0.71 | KMT2A (0.43) | KMT2ARIPK1 | |
| SCHEMBL18763097 | 0.71 | KMT2A (0.43) | KMT2ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535645-A2 | Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-07 | — | — | EP | disclosed |