Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | BMP1 | P13497 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846110 | 0.76 | CNR2 (0.37) | CNR2KEAP1NFE2L2BMP1MEN1 | |
| SCHEMBL7846527 | 0.75 | CNR2 (0.46) | CNR2KEAP1NFE2L2BMP1MEN1 | |
| SCHEMBL7846493 | 0.74 | ALDH1A1 (0.38) | CNR2MMP9MMP13MEN1KMT2A | |
| SCHEMBL7837755 | 0.74 | CNR2 (0.35) | CNR2KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL7846766 | 0.73 | CNR2 (0.40) | CNR2KEAP1NFE2L2BMP1MMP9 | |
| SCHEMBL7846307 | 0.73 | PKM (0.39) | BMP1MMP9MMP13MEN1KMT2A | |
| SCHEMBL7848583 | 0.72 | ALDH1A1 (0.38) | CNR2MMP13MEN1KMT2ALMNA | |
| SCHEMBL7846525 | 0.71 | CNR2 (0.40) | CNR2KEAP1NFE2L2MEN1KMT2A | |
| SCHEMBL7837233 | 0.71 | MEN1 (0.35) | CNR2BMP1MMP9MMP13MEN1 | |
| SCHEMBL7848884 | 0.71 | CNR2 (0.35) | CNR2BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |