Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048444 | 0.92 | P2RX3 (0.56) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2672364 | 0.89 | PGR (0.53) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL2672956 | 0.83 | NR3C1 (0.59) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL17917621 | 0.83 | HPGD (0.53) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL28178755 | 0.83 | ALDH1A1 (0.53) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL7834105 | 0.79 | ALDH1A1 (0.55) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL5253014 | 0.79 | HPGD (0.55) | ALDH1A1HPGDKDM4ESMN1; SMN2CYP3A4 | |
| SCHEMBL11680681 | 0.78 | TYMP (0.49) | TYMPALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL15180969 | 0.77 | P2RX3 (0.46) | TYMPSMN1; SMN2CYP3A4P2RX3MEN1 | |
| SCHEMBL7844750 | 0.75 | HPGD (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5840732-A | ANTIDIABETIC AGENTS, AUTOIMMUNE DISEASES OR IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |