SCHEMBL7847835

SCHEMBL7847835

CC(=O)Oc1cc(C)ccc1CCl

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
RAB9A P51151 3/20 0.42
NPC1 O15118 2/20 0.42
ALDH1A1 P00352 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
AKT1 P31749 1/20 0.41
ELANE P08246 1/20 0.41
HTT P42858 2/20 0.40
PKM P14618 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ACHE P22303 1/20 0.39
MAOB P27338 2/20 0.39
TSHR P16473 2/20 0.39
GAA P10253 1/20 0.39
CFD P00746 2/20 0.38
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8197650 0.86 LMNA (0.48) LMNARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL9222607 0.84 LMNA (0.50) LMNARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL7847833 0.83 LMNA (0.38) LMNAALDH1A1SMN1; SMN2HTTKDM4E
SCHEMBL21044063 0.83 LMNA (0.48) LMNARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL27345939 0.81 SMN1; SMN2 (0.39) LMNAALDH1A1SMN1; SMN2HTTKDM4E
SCHEMBL9314196 0.80 LMNA (0.46) LMNARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL809846 0.78 TRPA1 (0.41) LMNARAB9ANPC1SMN1; SMN2AKT1
SCHEMBL8350024 0.77 TSHR (0.60) LMNARAB9ANPC1ALDH1A1SMN1; SMN2
SCHEMBL7848040 0.77 PTGDR2 (0.54) LMNASMN1; SMN2HTTKDM4ETSHR
SCHEMBL8367844 0.77 ALDH1A1 (0.49) LMNARAB9ANPC1ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0656892-B1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORP (US) 2001-06-13 EP disclosed
EP-0656892-A1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1995-06-14 EP disclosed