SCHEMBL21044063

SCHEMBL21044063

CC(=O)Oc1cc(C)ccc1CBr

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.48
ALDH1A1 P00352 2/20 0.42
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CFD P00746 2/20 0.41
ELANE P08246 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
KDM4E B2RXH2 2/20 0.40
ACHE P22303 1/20 0.39
MAOB P27338 2/20 0.39
TSHR P16473 2/20 0.39
GAA P10253 1/20 0.39
CYP4F2 P78329 1/20 0.38
CYP4A11 Q02928 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9222607 0.84 LMNA (0.50) LMNAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL7847835 0.83 LMNA (0.48) LMNAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL8216520 0.83 CFD (0.49) LMNAALDH1A1RAB9ACFDKDM4E
SCHEMBL6650657 0.81 CYP4F2 (0.44) ALDH1A1RAB9ASMN1; SMN2CFDKDM4E
SCHEMBL9314196 0.80 LMNA (0.46) LMNAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL3639665 0.80 BACE1 (0.51) LMNAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL8897775 0.79 CFD (0.39) LMNAALDH1A1RAB9ACFDKDM4E
SCHEMBL9643353 0.79 HSD17B2 (0.51) LMNAALDH1A1RAB9ANPC1SMN1; SMN2
SCHEMBL1017686 0.78 RAB9A (0.52) ALDH1A1RAB9ANPC1SMN1; SMN2KDM4E
SCHEMBL27001734 0.78 GSK3B (0.39) ALDH1A1RAB9ACFDKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I (CZ) 2025-07-17 US disclosed
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR. V.V.I. (CZ) 2025-04-08 US disclosed
EP-3717466-B1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR V V I (CZ) 2022-01-05 EP disclosed
EP-3717466-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie a Biochemie AV CR, v.v.i. (CZ) 2020-10-07 EP disclosed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US disclosed
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I. (CZ) 2020-09-10 US disclosed
EP-3492460-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS, METHOD OF SEPARATION, AND USE THEREOF Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) 2019-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250229198-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCO2, SOD3, SLC39A3 LMNA 593/4885ALDH1A1 4085/4885RAB9A 1520/4885
US-20200282331-A1 COMPOUNDS FOR SEPARATION OF RARE EARTH ELEMENTS AND S-, P-, D- METALS, METHOD OF SEPARATION, AND USE THEREOF SCLY, SFXN1, PTCD3 LMNA 2040/4885ALDH1A1 2634/4885RAB9A 1629/4885
US-12268977-B2 Compounds for separation of rare earth elements and s-, p-, d-metals, method of separation, and use thereof SCLY, SFXN1, PTCD3 LMNA 2040/4885ALDH1A1 2634/4885RAB9A 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.