Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7838706 | 0.89 | ESR1 (0.39) | ESR1ESR2MCHR1F10ACHE | |
| SCHEMBL7850648 | 0.74 | ACHE (0.36) | ESR1ESR2ACHE | |
| SCHEMBL7227822 | 0.74 | MCHR1 (0.55) | ESR1ESR2MCHR1ACHEHDAC6 | |
| SCHEMBL7847330 | 0.73 | GPR119 (0.33) | GPR119 | |
| SCHEMBL7847331 | 0.73 | GPR119 (0.33) | GPR119 | |
| SCHEMBL7226191 | 0.69 | MCHR1 (0.51) | MCHR1ACHE | |
| SCHEMBL7850875 | 0.68 | ITGAV (0.30) | — | |
| SCHEMBL7850878 | 0.68 | ITGAV (0.30) | — | |
| SCHEMBL25604137 | 0.67 | ESR1 (0.48) | ESR1ESR2HDAC6 | |
| SCHEMBL2310767 | 0.67 | ESR1 (0.49) | ESR1ESR2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |