Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847331 | 1.00 | GPR119 (0.33) | GPR119CA12CA1CA2CA7 | |
| SCHEMBL7850878 | 0.78 | ITGAV (0.30) | — | |
| SCHEMBL7850875 | 0.78 | ITGAV (0.30) | — | |
| SCHEMBL7847874 | 0.73 | ESR1 (0.38) | GPR119 | |
| SCHEMBL7838706 | 0.72 | ESR1 (0.39) | — | |
| SCHEMBL7846900 | 0.72 | ACHE (0.38) | GPR119CYP11B2 | |
| SCHEMBL31733731 | 0.72 | PDK1 (0.45) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31733487 | 0.68 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31733772 | 0.68 | CA12 (0.39) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9205255 | 0.67 | ACHE (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |