Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784364 | 0.91 | F10 (0.39) | F10TLR9TLR8TLR7SPR | |
| SCHEMBL784593 | 0.91 | F10 (0.45) | PDK2F10TLR9TLR8TLR7 | |
| SCHEMBL784621 | 0.88 | UBE2M (0.37) | PDK2F10TLR9TLR8TLR7 | |
| SCHEMBL785542 | 0.88 | HPGD (0.44) | F10TLR9TLR8TLR7SPR | |
| SCHEMBL785276 | 0.85 | F10 (0.39) | F10TLR9TLR8TLR7SPR | |
| SCHEMBL785587 | 0.84 | RORC (0.43) | PDK2F10TLR9TLR8TLR7 | |
| SCHEMBL785840 | 0.83 | SPR (0.39) | PDK2F10TLR9TLR8TLR7 | |
| SCHEMBL784425 | 0.83 | F10 (0.40) | F10TLR9TLR8TLR7SPR | |
| SCHEMBL784539 | 0.83 | TLR9 (0.43) | PDK2F10TLR9TLR8TLR7 | |
| SCHEMBL785799 | 0.81 | TAF1 (0.42) | TLR9TLR8TLR7SPRMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | claimed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | claimed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | PDK2 2401/4885F10 524/4885TLR9 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.