Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.38 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.38 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848146 | 1.00 | L3MBTL1 (0.46) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8143558 | 0.94 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8143561 | 0.94 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27660159 | 0.94 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27660161 | 0.94 | L3MBTL1 (0.47) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28757793 | 0.85 | L3MBTL1 (0.51) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27639464 | 0.82 | TAS1R3 (0.46) | L3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL27639462 | 0.82 | TAS1R3 (0.46) | L3MBTL1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL7571102 | 0.81 | L3MBTL1 (0.53) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27639466 | 0.80 | CTSL (0.44) | ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105396-A1 | PROCESS FOR THE PREPARATION OF PYRROLO[2,3-D]PYRIMIDINES | The Trustees of Princeton University (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6066732-A | Process for the preparation of pyrrolo[2,3-d]pyrimidines | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |
| WO-2000011004-A1 | PROCESS FOR THE PREPARATION OF PYRROLO[2,3-D]PYRIMIDINES | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-03-02 | — | — | WO | disclosed |