SCHEMBL94584

SCHEMBL94584

O=C1C(=Cc2ccccc2)C2CCC1C2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.47
MAPT P10636 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C19 P33261 2/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
HPGD P15428 4/20 0.42
NFKB1 P19838 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
F3 P13726 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39
CHRNA4 P43681 1/20 0.39
CHRNA7 P36544 1/20 0.39
STK17B O94768 1/20 0.39
DUSP1 P28562 1/20 0.38
DUSP6 Q16828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4665877 1.00 CYP1A2 (0.47) CYP1A2MAPTCYP2D6CYP2C19LMNA
SCHEMBL14080306 0.90 MAPT (0.38) CYP1A2MAPTCYP2D6CYP2C19LMNA
SCHEMBL7839741 0.78 MEN1 (0.38) CYP1A2MAPTLMNASMN1; SMN2NPSR1
SCHEMBL1824532 0.77 TDP1 (0.42) CYP1A2MAPTCYP2D6CYP2C19LMNA
SCHEMBL13299668 0.76 NPC1 (0.50) CYP1A2MAPTSMN1; SMN2HPGDF3
SCHEMBL22667801 0.74
SCHEMBL7839790 0.73 ALDH1A1 (0.45) CYP1A2MAPTLMNASMN1; SMN2ALDH1A1
SCHEMBL7848396 0.69 MAPT (0.45) CYP1A2MAPTCYP2D6CYP2C19LMNA
SCHEMBL7848283 0.69 MAPT (0.45) CYP1A2MAPTCYP2D6CYP2C19LMNA
SCHEMBL9585267 0.68 CYP1A2 (0.52) CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 782 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108430448-B Emulsion containing UV sun protection factor and carnosine 西姆莱斯股份公司 2021-10-01 CN claimed
US-10857085-B2 Preparations comprising carnosines SYMRISE AG (DE) 2020-12-08 US claimed
US-10688032-B2 Emulsions having UV sunscreen factors and carnosines SYMRISE AG (DE) 2020-06-23 US claimed
US-20180369116-A1 PREPARATIONS COMPRISING CARNOSINES SYMRISE AG (DE) 2018-12-27 US claimed
US-20180360723-A1 EMULSIONS HAVING UV SUNSCREEN FACTORS AND CARNOSINES SYMRISE AG (DE) 2018-12-20 US claimed
EP-3389619-A1 PREPARATIONS COMPRISING CARNOSINES Symrise AG (DE) 2018-10-24 EP claimed
EP-3389621-A1 EMULSIONS HAVING UV SUNSCREEN FACTORS AND CARNOSINES Symrise AG (DE) 2018-10-24 EP claimed
US-20180221263-A1 MEDICAMENT SYMRISE AG (DE) 2018-08-09 US claimed
US-20160166488-A1 MEDICAMENT SYMRISE AG (DE) 2016-06-16 US claimed
EP-1296701-B1 USE OF GRIFOLA FRONDOSA FUNGUS EXTRACTS COGNIS FRANCE SAS (FR) 2009-09-30 EP claimed
EP-1162941-B1 SUN PROTECTION AGENTS BIOTEC PHARMACON ASA (NO) 2006-05-24 EP claimed
US-6500410-B1 IMPROVING THE PHOTO SENSITIVITY AND SOLUBILITY OF UV LIGHT PROTECTION FACTOR IN SUN PROTECTING AGENTS COMPRISING INCLUDING WATER SOLUBLE BETA-(1,3) GLUCANS WHICH ARE SUBSTANTIALLY FREE FROM BETA-(1,6) LINKAGES BIOTEC PHARMACON ASA (NO) 2002-12-31 US claimed
US-5730960-A SUNSCREEN AGENT MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-03-24 US claimed
EP-0693471-B1 Benzylidene-norcamphor derivatives MERCK PATENT GMBH (DE) 1998-01-21 EP claimed
EP-3801448-B1 WAX DISPERSIONS WITH CONDITIONING PROPERTIES BASF SE (DE) 2024-07-10 EP disclosed
EP-4376995-A1 BIOBASED CORE-SHELL MICROCAPSULES Symrise AG (DE) 2024-06-05 EP disclosed
EP-4366690-A1 POLYOL ESTER MIXTURE FOR USE AS VASELINE SUBSTITUTE BASF SE (DE) 2024-05-15 EP disclosed
US-5705169-A REACTING FORMYLBENZALDEHYDE WITH KETOTRICYCLODECANE; DRUGS, COSMETICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1998-01-06 US disclosed
EP-0693471-A1 Benzylidene-norcamphor derivatives MERCK PATENT GmbH (DE) 1996-01-24 EP disclosed
EP-0693471-A1 Benzylidene-norcamphor derivatives MERCK PATENT GmbH (DE) 1996-01-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180221263-A1 MEDICAMENT MMP2, MMP3, MMP10 CYP1A2 295/4885MAPT 3308/4885CYP2D6 782/4885
US-10688032-B2 Emulsions having UV sunscreen factors and carnosines F12, C1S, CCNI CYP1A2 917/4885MAPT 1825/4885CYP2D6 2144/4885
US-20180360723-A1 EMULSIONS HAVING UV SUNSCREEN FACTORS AND CARNOSINES F12, C1S, CCNI CYP1A2 917/4885MAPT 1825/4885CYP2D6 2144/4885
US-20180369116-A1 PREPARATIONS COMPRISING CARNOSINES C1R, C9, F12 CYP1A2 1625/4885MAPT 958/4885CYP2D6 3619/4885
US-10857085-B2 Preparations comprising carnosines C1R, C9, F12 CYP1A2 1625/4885MAPT 958/4885CYP2D6 3619/4885
US-20160166488-A1 MEDICAMENT MMP2, MMP3, MMP10 CYP1A2 295/4885MAPT 3308/4885CYP2D6 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.