Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7845257 | 0.89 | CNR1 (0.37) | CNR2KEAP1NFE2L2CNR1MEN1 | |
| SCHEMBL7846110 | 0.86 | CNR2 (0.37) | CNR2KEAP1NFE2L2CNR1MEN1 | |
| SCHEMBL7845578 | 0.84 | ACHE (0.31) | CNR2APLNRMEN1KMT2A | |
| SCHEMBL7845845 | 0.84 | KMT2A (0.34) | CNR1MEN1KMT2A | |
| SCHEMBL7837755 | 0.81 | CNR2 (0.35) | CNR2KEAP1NFE2L2CNR1APLNR | |
| SCHEMBL7837399 | 0.78 | NR1I2 (0.34) | CNR2KEAP1NFE2L2 | |
| SCHEMBL7846525 | 0.77 | CNR2 (0.40) | CNR2KEAP1NFE2L2CNR1MEN1 | |
| SCHEMBL7849225 | 0.76 | EDNRB (0.33) | CNR2CNR1APLNRMEN1KMT2A | |
| SCHEMBL6200975 | 0.73 | CNR2 (0.33) | CNR2KEAP1NFE2L2CNR1APLNR | |
| SCHEMBL7846237 | 0.73 | APP (0.34) | CNR2CNR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | disclosed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | disclosed |