Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | HPD | P32754 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846575 | 0.89 | HPD (0.41) | MAPTPOLBSMN1; SMN2P2RX3HPD | |
| SCHEMBL7848710 | 0.85 | MTNR1A (0.37) | MAPTLMNASMN1; SMN2TP53BACE1 | |
| SCHEMBL7848458 | 0.83 | MAPT (0.36) | MAPTLMNAPOLBRXFP1SMN1; SMN2 | |
| SCHEMBL6086806 | 0.83 | KMT2A (0.34) | MAPTLMNAPOLBRXFP1SMN1; SMN2 | |
| SCHEMBL7837543 | 0.81 | GRIN1 (0.43) | POLBMEN1MAPK10KMT2A | |
| SCHEMBL7846719 | 0.81 | TYMS (0.41) | P2RX3ALDH1A1 | |
| SCHEMBL7847828 | 0.81 | MEN1 (0.33) | MAPTSMN1; SMN2TP53ALDH1A1MEN1 | |
| SCHEMBL7847168 | 0.81 | MTNR1A (0.49) | MAPTPOLBTP53ALDH1A1KMT2A | |
| SCHEMBL7836190 | 0.81 | MAPT (0.36) | MAPTLMNASMN1; SMN2P2RX3HPD | |
| SCHEMBL7836192 | 0.80 | KDM5B (0.32) | POLBP2RX3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |