Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.70 |
| ▸ | HTR2B | P41595 | 5/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7850655 | 0.91 | HDAC3 (0.61) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| SCHEMBL7846238 | 0.88 | ACHE (0.59) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| SCHEMBL7848672 | 0.86 | HDAC3 (0.56) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| SCHEMBL7849523 | 0.85 | HDAC3 (0.57) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL7846330 | 0.84 | HDAC3 (0.56) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| SCHEMBL6802856 | 0.83 | HTR7 (0.58) | HTR2CHTR2BACHEKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6798090 | 0.82 | HTR7 (0.57) | HTR2CHTR2BACHEKMT2ASMN1; SMN2 | |
| SCHEMBL7848854 | 0.82 | HDAC3 (0.57) | HTR2CHTR2BHDAC3HDAC4HDAC1 | |
| SCHEMBL7848867 | 0.80 | KMT2A (0.51) | HTR2CHTR2BACHEKMT2ASMN1; SMN2 | |
| SCHEMBL28364961 | 0.78 | ALDH1A1 (0.65) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1122252-A1 | NITROGENOUS FUSED HETEROCYCLE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND AGENTS CONTAINING THE SAME | Takeda Chemical Industries, Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |