Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 10/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848640 | 0.82 | RXRA (0.42) | GAAALDH1A1 | |
| SCHEMBL11665507 | 0.82 | GPBAR1 (0.55) | GPBAR1CYSLTR1GAAHSD17B10MTNR1A | |
| SCHEMBL7848555 | 0.79 | ACACB (0.38) | GPBAR1CYSLTR1MTNR1AMTNR1BMCHR1 | |
| SCHEMBL10249607 | 0.77 | OGG1 (0.51) | GPBAR1CYSLTR1ALDH1A1MAPT | |
| SCHEMBL19665952 | 0.77 | GPBAR1 (0.46) | GPBAR1CYSLTR1GAAHSD17B10MTNR1A | |
| SCHEMBL2092088 | 0.77 | GPBAR1 (0.48) | GPBAR1CYSLTR1GAAHSD17B10MTNR1A | |
| SCHEMBL13791767 | 0.75 | MTNR1A (0.59) | GPBAR1CYSLTR1MTNR1AMTNR1BTSHR | |
| SCHEMBL21225856 | 0.75 | DRD1 (0.42) | GAAMAPT | |
| SCHEMBL13791121 | 0.75 | ACHE (0.50) | GPBAR1CYSLTR1GAAHSD17B10ALDH1A1 | |
| SCHEMBL13791679 | 0.75 | MTNR1A (0.59) | GPBAR1CYSLTR1MTNR1AMTNR1BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |