SCHEMBL7848628

SCHEMBL7848628

CC1CC(=O)C2CC1C2(C)C

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.53
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
CRBN Q96SW2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18199897 1.00 CES2 (0.53) CES2KDM4EALDH1A1CRBN
SCHEMBL23903712 1.00 CES2 (0.53) CES2KDM4EALDH1A1CRBN
SCHEMBL10013211 0.83 CES2 (0.49) CES2KDM4EALDH1A1CRBN
SCHEMBL16077505 0.79 CES2 (0.42) CES2KDM4EALDH1A1
SCHEMBL2762976 0.77 CES2 (0.51) CES2KDM4EALDH1A1
SCHEMBL23903709 0.74 CES2 (0.33) CES2
SCHEMBL9219881 0.74 CES2 (0.33) CES2
SCHEMBL3303780 0.72 CES2 (0.47) CES2
SCHEMBL16079422 0.69 ALDH1A1 (0.49) CES2ALDH1A1
SCHEMBL16079419 0.69 CES2 (0.34) CES2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220133616-A1 Compositions, Methods and Uses for Treating Skin Aging EVANS ROBIN JAMES (US) 2022-05-05 US claimed
EP-0754445-B1 Photostable cosmetic light screening compositions HOFFMANN LA ROCHE (CH) 2001-10-24 EP claimed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP claimed
EP-3244930-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIV SOUTHERN CALIFORNIA (US) 2026-05-06 EP disclosed
US-20260083685-A1 METHODS OF PERMEABILIZING THE BLOOD BRAIN BARRIER UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2026-03-26 US disclosed
US-20260069587-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2026-03-12 US disclosed
US-12514828-B2 Methods of permeabilizing the blood brain barrier UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2026-01-06 US disclosed
EP-4656641-A2 METHODS AND DEVICES FOR USING ISOPERILLYL ALCOHOL University of Southern California (US) 2025-12-03 EP disclosed
US-20250332262-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-10-30 US disclosed
US-12383621-B2 Pharmaceutical compositions comprising POH derivatives UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2025-08-12 US disclosed
US-20250186472-A1 COMBINATION OF POH AND REMDESIVIR FOR TREATMENT OF CNS INFECTIONS Neonc Technologies, Inc. 2025-06-12 US disclosed
US-20220054481-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL UNIVERSITY OF SOUTHERN CALIFORNIA 2022-02-24 US disclosed
WO-2016180973-A1 PYROLYTIC METHOD FOR THE PRODUCTION OF PARTICLES CONTAINING AT LEAST ONE METAL SPECIES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-11-17 WO disclosed
EP-2123264-A1 Heterocyclic derivatives as abnormal cannabidiols agents for lowering intraocular pressure Allergan, Inc. (US) 2009-11-25 EP disclosed
WO-2007127711-A2 ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE ALLERGAN, INC. (US) 2007-11-08 WO disclosed
US-20070249596-A1 ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE ALLERGAN, INC. 2007-10-25 US disclosed
US-20070249596-A1 ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE ALLERGAN, INC. 2007-10-25 US disclosed
EP-0754445-B1 Photostable cosmetic light screening compositions HOFFMANN LA ROCHE (CH) 2001-10-24 EP disclosed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP disclosed
EP-0754445-A2 Photostable cosmetic light screening compositions GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) 1997-01-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070249596-A1 ABNORMAL CANNABIDIOLS AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE CNR2, CNR1, PTGIR CES2 3575/4885KDM4E 1564/4885ALDH1A1 3297/4885
US-12383621-B2 Pharmaceutical compositions comprising POH derivatives PDE3A, PDE3B, PDE5A CES2 403/4885KDM4E 215/4885ALDH1A1 205/4885
US-20220133616-A1 Compositions, Methods and Uses for Treating Skin Aging GLA, TERT, CUTA CES2 1225/4885KDM4E 965/4885ALDH1A1 306/4885
US-20250186472-A1 COMBINATION OF POH AND REMDESIVIR FOR TREATMENT OF CNS INFECTIONS CFH, AQP4, MAG CES2 345/4885KDM4E 1282/4885ALDH1A1 2939/4885
US-20220054481-A1 METHODS OF TREATING NEUROFIBROMATOSIS WITH PERILLYL ALCOHOL PMP22, CHAT, REL CES2 532/4885KDM4E 911/4885ALDH1A1 46/4885
US-20260069587-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES GCDH, PLIN3, PRPH CES2 87/4885KDM4E 1771/4885ALDH1A1 400/4885
US-20250332262-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POH DERIVATIVES PDE3A, PDE3B, PDE5A CES2 403/4885KDM4E 215/4885ALDH1A1 205/4885
US-20260083685-A1 METHODS OF PERMEABILIZING THE BLOOD BRAIN BARRIER CD4, EPCAM, ICOS CES2 323/4885KDM4E 3878/4885ALDH1A1 1230/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.