Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637883 | 0.81 | EPHX2 (0.62) | ALDH1A1KMT2AEPHX2CA12CA1 | |
| SCHEMBL7371442 | 0.79 | EPHX2 (0.64) | LMNAALDH1A1KMT2AEPHX1EPHX2 | |
| SCHEMBL4116189 | 0.74 | HDAC4 (0.52) | CA12CA1CA2MMP2MMP9 | |
| SCHEMBL4711538 | 0.74 | HDAC4 (0.52) | CA12CA1CA2MMP2MMP9 | |
| SCHEMBL4760506 | 0.74 | HDAC4 (0.52) | CA12CA1CA2MMP2MMP9 | |
| SCHEMBL9701078 | 0.74 | HDAC4 (0.52) | CA12CA1CA2MMP2MMP9 | |
| SCHEMBL9539183 | 0.72 | MMP2 (0.53) | LMNAALDH1A1GAAKDM4EKMT2A | |
| SCHEMBL14851122 | 0.72 | SMN1; SMN2 (0.56) | LMNAALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL14855962 | 0.72 | SMN1; SMN2 (0.56) | LMNAALDH1A1GAAKMT2AEPHX2 | |
| SCHEMBL4064616 | 0.71 | ALDH1A1 (0.51) | LMNAALDH1A1GAASMN1; SMN2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091932-A1 | CHIRAL STATIONARY PHASES FOR ENANTIOMERS SEPARATION AND THEIR PREPARATION | Societa' Cooperativa Centro Ricerche Poly-Tech a Responsabilita' Limitata (IT) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000000464-A1 | CHIRAL STATIONARY PHASES FOR ENANTIOMERS SEPARATION AND THEIR PREPARATION | SOCIETA' COOPERATIVA CENTRO RICERCHE POLY-TECH A RESPONSABILITA' LIMITATA (IT) | 2000-01-06 | — | — | WO | disclosed |