Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 7/20 | 0.41 |
| ▸ | MGAM | O43451 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SI | P14410 | 3/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.40 |
| ▸ | MC5R | P33032 | 2/20 | 0.40 |
| ▸ | MC1R | Q01726 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847455 | 0.79 | TACR1 (0.43) | MAOBMEN1MAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL27785466 | 0.78 | GABRP (0.47) | MEN1MAPTKMT2AMGAMGAA | |
| SCHEMBL7848664 | 0.78 | MC5R (0.61) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27763685 | 0.74 | HTR2A (0.49) | MEN1MAPTKMT2AMGAMGAA | |
| SCHEMBL7856881 | 0.74 | TACR1 (0.57) | MEN1KMT2APOLBTACR1MGAM | |
| SCHEMBL27763691 | 0.68 | MGAM (0.52) | MEN1MAPTKMT2AMGAMGAA | |
| SCHEMBL7846982 | 0.68 | BRS3 (0.60) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL7062961 | 0.68 | TACR1 (0.76) | MEN1KMT2ATACR1 | |
| SCHEMBL7848666 | 0.68 | MAPT (0.53) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27777642 | 0.68 | GPR84 (0.56) | MEN1MAPTKMT2AMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140914-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000037462-A1 | NON-PEPTIDE NK1 RECEPTORS ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 2000-06-29 | — | — | WO | disclosed |