Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL784756 | 0.85 | F10 (0.40) | F10NPC1RAB9ACCR5POLB | |
| SCHEMBL785183 | 0.84 | F10 (0.39) | F10NPC1RAB9ACCR5POLB | |
| SCHEMBL785118 | 0.83 | MCHR1 (0.44) | F10CCR5ALDH1A1ALOX15POLB | |
| SCHEMBL785119 | 0.83 | MCHR1 (0.44) | F10CCR5ALDH1A1ALOX15POLB | |
| SCHEMBL784197 | 0.82 | NPC1 (0.43) | F10NPC1RAB9ACCR5ALDH1A1 | |
| SCHEMBL784391 | 0.82 | ROCK2 (0.38) | F10NPC1RAB9ACCR5ROCK2 | |
| SCHEMBL784878 | 0.82 | ACHE (0.43) | F10CCR5ALDH1A1ALOX15POLB | |
| SCHEMBL786045 | 0.81 | CCR5 (0.42) | F10CCR5ALDH1A1ALOX15POLB | |
| SCHEMBL785450 | 0.81 | F10 (0.39) | F10NPC1RAB9ACCR5ROCK2 | |
| SCHEMBL785435 | 0.81 | F10 (0.39) | F10NPC1RAB9ACCR5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | F10 524/4885NPC1 2033/4885RAB9A 1673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.