Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850984 | 0.92 | KMT2A (0.63) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9218202 | 0.87 | MAPT (0.55) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9209028 | 0.87 | NPC1 (0.77) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL7848711 | 0.83 | LMNA (0.64) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9312633 | 0.83 | LMNA (0.64) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL9211658 | 0.80 | MAPT (0.68) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL10531019 | 0.80 | LTC4S (0.62) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL28968013 | 0.79 | MAPT (0.67) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL22166431 | 0.78 | KMT2A (0.72) | LMNAMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL19409872 | 0.77 | MAPT (0.73) | LMNAMEN1CYP1A2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0266310-B1 | Chromogenic phthalides | CIBA SC HOLDING AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| EP-0437185-B1 | Pyrroline-resp. indoline containing phthalides | CIBA GEIGY AG (CH) | 1995-10-18 | — | — | EP | disclosed |
| EP-0420808-B1 | Pyran-containing phthalides | CIBA GEIGY AG (CH) | 1995-03-01 | — | — | EP | disclosed |
| EP-0437185-A2 | Pyrroline-resp. indoline containing phthalides | CIBA-GEIGY AG (CH) | 1991-07-17 | — | — | EP | disclosed |
| EP-0420808-A2 | Pyran-containing phthalides | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |