Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 12/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850053 | 0.85 | GRIN1 (0.49) | GRIN1GRIN2BRXFP1DPP4NOX4 | |
| SCHEMBL6087771 | 0.84 | GRIN1 (0.50) | GRIN1GRIN2BRXFP1DPP4NOX4 | |
| SCHEMBL8189652 | 0.83 | KDM4E (0.45) | — | |
| SCHEMBL7845869 | 0.80 | GRIN1 (0.50) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL7847258 | 0.79 | ALDH1A1 (0.34) | GRIN1GRIN2B | |
| SCHEMBL7847796 | 0.79 | GRIN1 (0.49) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL7836586 | 0.76 | HSD17B10 (0.51) | GRIN1GRIN2BTP53 | |
| SCHEMBL7847304 | 0.76 | GRIN1 (0.44) | GRIN1GRIN2BNOX4 | |
| SCHEMBL6086571 | 0.75 | GRIN1 (0.49) | GRIN1GRIN2BRXFP1DPP4NOX4 | |
| SCHEMBL7837064 | 0.75 | HSD17B10 (0.39) | GRIN1GRIN2BTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |