Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 13/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 13/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6087771 | 0.85 | GRIN1 (0.50) | GRIN1GRIN2BDPP4RXFP1NOX4 | |
| SCHEMBL7850053 | 0.84 | GRIN1 (0.49) | GRIN1GRIN2BDPP4RXFP1NOX4 | |
| SCHEMBL6086817 | 0.83 | HPGD (0.43) | — | |
| SCHEMBL6087484 | 0.82 | GRIN1 (0.43) | GRIN1GRIN2B | |
| SCHEMBL6087882 | 0.80 | GRIN1 (0.49) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL6087128 | 0.80 | TPH1 (0.34) | GRIN1GRIN2BTP53 | |
| SCHEMBL6087068 | 0.80 | DAO (0.46) | — | |
| SCHEMBL6086789 | 0.80 | GRIN1 (0.48) | GRIN1GRIN2BDPP4NOX4 | |
| SCHEMBL6087193 | 0.78 | ROCK2 (0.36) | GRIN1GRIN2BDPP4RXFP1 | |
| SCHEMBL6088257 | 0.78 | NPBWR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6987114-B1 | Antiviral pyrimidinedione derivatives and process for the preparation thereof | SAMJIN PHARMACEUTICAL CO., LTD (KR) | 2006-01-17 | — | — | US | disclosed |