Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183668 | 0.86 | ALDH1A1 (0.42) | KMT2ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL7843309 | 0.84 | HSD17B10 (0.38) | GRIN1GRIN2BKMT2AROCK2ALDH1A1 | |
| SCHEMBL7849648 | 0.83 | GRIN1 (0.36) | GRIN1GRIN2BKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6086770 | 0.82 | GRIN1 (0.37) | GRIN1GRIN2BKMT2AGAASMN1; SMN2 | |
| SCHEMBL7848121 | 0.80 | HSD17B10 (0.49) | GRIN1GRIN2BKMT2AALDH1A1KDM4E | |
| SCHEMBL7836833 | 0.79 | GRIN1 (0.41) | GRIN1GRIN2BKMT2AROCK2 | |
| SCHEMBL7844403 | 0.77 | GRIN1 (0.37) | GRIN1GRIN2BKMT2AGAAROCK2 | |
| SCHEMBL7846972 | 0.77 | CYP1A2 (0.34) | KMT2AGAASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL7847397 | 0.77 | GRIN1 (0.43) | GRIN1GRIN2BKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7845884 | 0.76 | GRIN1 (0.36) | GRIN1GRIN2BKMT2AGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |