Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE1A | P54750 | 1/20 | 0.38 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848132 | 0.85 | GRIN1 (0.40) | GRIN1GRIN2BIDH1POLBROCK2 | |
| SCHEMBL8183668 | 0.85 | ALDH1A1 (0.42) | POLBKMT2A | |
| SCHEMBL6087278 | 0.84 | GRIN1 (0.41) | GRIN1GRIN2BIDH1POLBROCK2 | |
| SCHEMBL7848121 | 0.83 | HSD17B10 (0.49) | GRIN1GRIN2BPOLBKMT2A | |
| SCHEMBL7845869 | 0.82 | GRIN1 (0.50) | GRIN1GRIN2BDPP4 | |
| SCHEMBL7848958 | 0.79 | GRIN1 (0.37) | GRIN1GRIN2BROCK2KMT2A | |
| SCHEMBL9009383 | 0.78 | NOX4 (0.37) | GRIN1 | |
| SCHEMBL7843309 | 0.77 | HSD17B10 (0.38) | GRIN1GRIN2BPOLBROCK2KMT2A | |
| SCHEMBL7846972 | 0.76 | CYP1A2 (0.34) | POLBKMT2A | |
| SCHEMBL7848188 | 0.76 | TLR7 (0.33) | GRIN1GRIN2BPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |