Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 3/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CD74 | P04233 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7843309 | 0.91 | HSD17B10 (0.38) | HSD17B10MTNR1AMTNR1BMIFGRIN1 | |
| SCHEMBL8183668 | 0.86 | ALDH1A1 (0.42) | MIFPOLBALDH1A1CD74KMT2A | |
| SCHEMBL7837651 | 0.85 | MTNR1A (0.50) | HSD17B10MTNR1AMTNR1BMIFGRIN1 | |
| SCHEMBL6087289 | 0.84 | MTNR1A (0.48) | HSD17B10MTNR1AMTNR1BMIFGRIN1 | |
| SCHEMBL7836833 | 0.83 | GRIN1 (0.41) | GRIN1GRIN2BPOLBKMT2A | |
| SCHEMBL7836586 | 0.81 | HSD17B10 (0.51) | HSD17B10MTNR1AMTNR1BMIFGRIN1 | |
| SCHEMBL7848958 | 0.80 | GRIN1 (0.37) | HSD17B10GRIN1GRIN2BALDH1A1KMT2A | |
| SCHEMBL7849696 | 0.79 | HSD17B10 (0.48) | HSD17B10MTNR1AMTNR1BMIFGRIN1 | |
| SCHEMBL9009456 | 0.77 | ALDH1A1 (0.46) | HSD17B10POLBALDH1A1L3MBTL1KMT2A | |
| SCHEMBL7846972 | 0.77 | CYP1A2 (0.34) | POLBALDH1A1KMT2ATSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |