Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.33 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183668 | 0.85 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2POLB | |
| SCHEMBL6086995 | 0.83 | POLB (0.35) | CYP1A2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7845277 | 0.80 | GRIN1 (0.45) | KDM4EALDH1A1HPGD | |
| SCHEMBL7848188 | 0.78 | TLR7 (0.33) | CYP1A2KDM4EALDH1A1DHFRNOTUM | |
| SCHEMBL7845869 | 0.78 | GRIN1 (0.50) | — | |
| SCHEMBL7836075 | 0.78 | RAB9A (0.38) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL7848121 | 0.77 | HSD17B10 (0.49) | CYP1A2KDM4EALDH1A1HPGDPOLB | |
| SCHEMBL7848958 | 0.77 | GRIN1 (0.37) | KDM4EALDH1A1HPGDSMN1; SMN2GAA | |
| SCHEMBL9009456 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1HPGDPOLBMEN1 | |
| SCHEMBL7836833 | 0.76 | GRIN1 (0.41) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |