SCHEMBL784936

SCHEMBL784936

CC(C)(C)c1cc(C(=O)c2ccc(O)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.58
PTGS1 P23219 1/20 0.58
PTGS2 P35354 1/20 0.58
LMNA P02545 3/20 0.56
HTT P42858 2/20 0.56
MAPT P10636 2/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
PKM P14618 1/20 0.56
HPGD P15428 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.50
ELANE P08246 1/20 0.50
GAA P10253 2/20 0.49
RECQL P46063 1/20 0.49
SRD5A2 P31213 1/20 0.48
MMP2 P08253 1/20 0.47
MMP3 P08254 1/20 0.47
MAPK1 P28482 1/20 0.47
CA2 P00918 2/20 0.47
CA1 P00915 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8495448 0.88 ALOX5 (0.65) ALOX5PTGS1PTGS2LMNAHTT
SCHEMBL16478410 0.87 LMNA (0.54) ALOX5PTGS1PTGS2LMNAHTT
SCHEMBL13057529 0.87 ALDH1A1 (0.57) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL8461116 0.87 SRD5A2 (0.59) ALOX5PTGS1PTGS2LMNAPKM
SCHEMBL10449344 0.86 ALOX5 (0.55) ALOX5PTGS1PTGS2LMNAHTT
SCHEMBL10449346 0.86 ALOX5 (0.55) ALOX5PTGS1PTGS2LMNAHTT
SCHEMBL10449867 0.86 PTGS1 (0.55) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL9135750 0.85 PTGS2 (0.63) ALOX5PTGS1PTGS2LMNASMN1; SMN2
SCHEMBL9621753 0.83 ALOX5 (0.53) ALOX5PTGS1PTGS2LMNAMAPT
SCHEMBL11531709 0.83 CA1 (0.58) ALOX5PTGS1PTGS2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007064843-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2007-06-07 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed
EP-0211548-B1 ANTIALLERGIC AGENTS RIKER LABORATORIES, INCORPORATED (US) 1990-05-09 EP disclosed
US-4165383-A BENZOYL-2,6-DI(T-BUTYL)PHENOL AND DERIVATIVES RIKER LABORATORIES, INC. (US) 1979-08-21 US disclosed
US-4124725-A ADMINISTERING A 4-(AMINOBENZOYL)-2,6-DI-TERT-BUTYLPHENOL RIKER LABORATORIES, INC. (US) 1978-11-07 US disclosed