Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL945282 | 0.75 | ACHE (0.34) | CA9CYP3A4MAPT | |
| SCHEMBL7286813 | 0.75 | ACHE (0.30) | — | |
| SCHEMBL312352 | 0.74 | CA12 (0.36) | CA12CA1CA2CA4CA7 | |
| SCHEMBL76231 | 0.74 | ACHE (0.48) | CA12CA1CA2CA4CA7 | |
| SCHEMBL6196771 | 0.74 | APP (0.38) | CA12CA1CA2CA4CA7 | |
| SCHEMBL499678 | 0.72 | CA12 (0.35) | CA12CA1CA2CA4CA7 | |
| SCHEMBL392541 | 0.72 | LMNA (0.43) | CA12CA1CA2CA4CA7 | |
| SCHEMBL28681440 | 0.72 | L3MBTL1 (0.41) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1578724 | 0.72 | MAPT (0.38) | CA12CA1CA2CA4CA7 | |
| SCHEMBL2287605 | 0.72 | CA12 (0.35) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714898-B1 | PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE | OTSUKA PHARMA CO LTD (JP) | 2001-11-14 | — | — | EP | disclosed |
| CN-1046730-C | Pyrazolo [1,5-a ] pyrimidine derivatives | OTSUKA PHARMA CO LTD (JP) | 1999-11-24 | — | — | CN | disclosed |
| US-5707997-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-13 | — | — | US | disclosed |
| CN-1131948-A | Pyrazolo [1, 5-a ] pyrimidine derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-25 | — | — | CN | disclosed |
| EP-0714898-A1 | PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-06-05 | — | — | EP | disclosed |