Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.30 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741240 | 0.94 | CA2 (0.35) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL9068216 | 0.88 | CA2 (0.35) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL15504703 | 0.85 | ALDH1A1 (0.33) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL2741247 | 0.85 | ALDH1A1 (0.33) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL8106600 | 0.84 | CA2 (0.36) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL784967 | 0.84 | CA2 (0.36) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL7907472 | 0.84 | CA2 (0.36) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL11529852 | 0.83 | ALDH1A1 (0.32) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL20558662 | 0.81 | CA2 (0.35) | CA2SMN1; SMN2ALDH1A1POLBTYR | |
| SCHEMBL15504699 | 0.79 | POLB (0.30) | CA2SMN1; SMN2ALDH1A1POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9523060-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150159109-A1 | Lubricant Oil Compositions | POLNOX CORPORATION | 2015-06-11 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8927472-B2 | Lubricant oil compositions | POLNOX CORPORATION (US) | 2015-01-06 | — | — | US | disclosed |
| US-8691933-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2014-04-08 | — | — | US | disclosed |
| US-20140011901-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2014-01-09 | — | — | US | disclosed |
| US-8481670-B2 | Stabilized polyolefin compositions | POLNOX CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |
| US-20130130955-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130130955-A1 | LUBRICANT OIL COMPOSITIONS | POLNOX CORPORATION (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130072586-A1 | Stabilized Polyolefin Compositions | POLNOX CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| US-7601378-B2 | Polymeric antioxidants | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2009-10-13 | — | — | US | disclosed |
| US-7595074-B2 | Polymeric antioxidants | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2009-09-29 | — | — | US | disclosed |
| US-7507454-B2 | Polymeric antioxidants | UNIVERSITY OF MASSACHUSETTS LOWELL (US) | 2009-03-24 | — | — | US | disclosed |
| US-20080293856-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-20070161522-A1 | Lubricant oil compositions | POLNOX CORPORATION | 2007-07-12 | — | — | US | disclosed |
| US-20070154430-A1 | Polymeric antioxidants | MASSACHUSETTS LOWELL, UNIVERSITY OF | 2007-07-05 | — | — | US | disclosed |
| US-20070154608-A1 | Antioxidant preservatives to increase the shelf life and palatability of lipid-containing foods and other products containing moieties (e.g., unsaturated carbon-carbon bonds) that can be damaged by free radicals; hydroxy substituted benzene polymers | UNIVERSITY OF MASSACHUSETTS LOWELL | 2007-07-05 | — | — | US | disclosed |
| US-20070154720-A1 | Polymeric antioxidants | CHOLLI ASHOK L | 2007-07-05 | — | — | US | disclosed |
| US-20070149660-A1 | Stabilized polyolefin compositions | POLNOX CORPORATION | 2007-06-28 | — | — | US | disclosed |
| US-7223432-B2 | Polymeric antioxidants | University of Massachusettes Lowell (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154430-A1 | Polymeric antioxidants | GPX4, NQO1, LPO | CA2 4508/4885SMN1; SMN2 1611/4885ALDH1A1 287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.