Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6088103 | 0.93 | ROCK2 (0.36) | ROCK2HTR6CYP2C9CYP2C19DDR1 | |
| SCHEMBL7854341 | 0.84 | TPH1 (0.33) | KDM4EMEN1KMT2A | |
| SCHEMBL7854092 | 0.83 | ROCK2 (0.32) | ROCK2 | |
| SCHEMBL7855333 | 0.81 | NR3C1 (0.35) | KDM4EMEN1KMT2A | |
| SCHEMBL7849218 | 0.79 | GRIN1 (0.39) | GRIN1GRIN2BMEN1ALDH1A1KMT2A | |
| SCHEMBL7853689 | 0.78 | TYMS (0.40) | DDR1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL6087118 | 0.78 | ROCK2 (0.34) | ROCK2CYP2C9CYP2C19DDR1GRIN1 | |
| SCHEMBL7853690 | 0.77 | PDE10A (0.36) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6086770 | 0.77 | GRIN1 (0.37) | ROCK2GRIN1GRIN2BALDH1A1KMT2A | |
| SCHEMBL6086545 | 0.76 | HPGD (0.43) | KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |