Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 3/20 | 0.36 |
| ▸ | MC5R | P33032 | 3/20 | 0.36 |
| ▸ | MC3R | P41968 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8184438 | 0.94 | PTPN1 (0.35) | MC4RMC5RMC3RPTPN1NPC1 | |
| SCHEMBL8175842 | 0.90 | SCN9A (0.32) | MC4RMC5RMC3RRAB9ASMN1; SMN2 | |
| SCHEMBL8173656 | 0.89 | MC4R (0.35) | MC4RMC5RMC3RPTPN1NPC1 | |
| SCHEMBL8162352 | 0.89 | MTNR1A (0.36) | MC4RMC5RMC3RGAAMAPT | |
| SCHEMBL8169206 | 0.81 | ALOX5 (0.35) | MAPTCACNA1B | |
| SCHEMBL8169630 | 0.78 | TRPM8 (0.36) | GAATDP1KDM4EALDH1A1ERAP2 | |
| SCHEMBL7850398 | 0.75 | POLB (0.44) | POLBKMT2A | |
| Trifluoroacetic Acid SCHEMBL7850378 | 0.74 | MC4R (0.47) | MC4RMC5RMC3RPTPN1PPARA | |
| SCHEMBL7857056 | 0.74 | POLB (0.34) | ERAP2LNPEPPOLB | |
| SCHEMBL7850343 | 0.73 | MC4R (0.42) | MC4RMC5RMC3RNPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |