Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8165236 | 0.93 | MC4R (0.43) | LTA4HLNPEPERAP2MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL8163599 | 0.91 | LTA4H (0.44) | LTA4HMEN1KMT2AITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7859146 | 0.84 | LNPEP (0.48) | LTA4HLNPEPERAP2ERAP1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8165238 | 0.81 | MC4R (0.43) | LTA4HLNPEPERAP2MAPK1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL8163602 | 0.81 | MMP2 (0.42) | LTA4HMAPK1ITGB3ITGA2BMMP2 | |
| Trifluoroacetic Acid SCHEMBL7860786 | 0.78 | KDM4E (0.43) | LTA4HMEN1KMT2AHTTITGB3 | |
| SCHEMBL7859103 | 0.77 | LNPEP (0.52) | LTA4HLNPEPERAP2ERAP1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL7850378 | 0.76 | MC4R (0.47) | LTA4HITGB3ITGA2BPTPN1PPARG | |
| Trifluoroacetic Acid SCHEMBL7860829 | 0.76 | LNPEP (0.44) | LNPEPERAP2MEN1KMT2AHTT | |
| Trifluoroacetic Acid SCHEMBL8169348 | 0.75 | MMP2 (0.42) | MMP2MC4RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |