Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 3/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 3/20 | 0.34 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851526 | 0.86 | EPHA2 (0.36) | LMNAKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL7849978 | 0.86 | GABRA2 (0.39) | LMNAKCNH2MEN1KMT2A | |
| SCHEMBL7850887 | 0.85 | LMNA (0.47) | LMNAKDM4EKCNH2PIM1MEN1 | |
| SCHEMBL9048087 | 0.83 | KDM4E (0.41) | LMNAKDM4EKCNH2PIM1MEN1 | |
| SCHEMBL8695477 | 0.79 | HTT (0.47) | LMNAKCNH2MEN1KMT2AALDH1A1 | |
| SCHEMBL7851459 | 0.78 | EPHA2 (0.36) | LMNAKDM4EKMT2AALDH1A1HPGD | |
| SCHEMBL6211209 | 0.76 | LMNA (0.37) | LMNAKDM4EKCNH2PIM1METTL3 | |
| SCHEMBL7840872 | 0.76 | KDM4E (0.34) | KDM4E | |
| SCHEMBL6213803 | 0.75 | ALDH1A1 (0.50) | LMNAKDM4EPIM1MEN1KMT2A | |
| SCHEMBL6215098 | 0.75 | PIM1 (0.43) | LMNAKDM4EPIM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | claimed |
| EP-0726270-B1 | Derivatives of 1,6-naphthyridone carboxylic acids | BAYER AG (DE) | 2001-05-23 | — | — | EP | disclosed |
| EP-0726270-A1 | Derivatives of 1,6-naphthyridine carboxylic acids | BAYER AG (DE) | 1996-08-14 | — | — | EP | disclosed |