Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 6/20 | 0.39 |
| ▸ | JAK1 | P23458 | 6/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786234 | 0.90 | CCR5 (0.40) | MCHR1F10POLBCCR5JAK2 | |
| SCHEMBL785875 | 0.89 | MCHR1 (0.39) | MCHR1F10POLBCCR5JAK2 | |
| SCHEMBL784767 | 0.88 | MCHR1 (0.38) | MCHR1F10POLBCCR5JAK2 | |
| SCHEMBL28805786 | 0.88 | ACHE (0.46) | ACHEMCHR1F10POLBCCR5 | |
| SCHEMBL784928 | 0.87 | TLR9 (0.43) | ACHEF10POLBJAK2JAK1 | |
| SCHEMBL785446 | 0.87 | CTSS (0.52) | MCHR1POLBCCR5JAK2JAK1 | |
| SCHEMBL784410 | 0.87 | POLB (0.41) | ACHEMCHR1F10POLBCCR5 | |
| SCHEMBL785829 | 0.86 | F10 (0.41) | ACHEMCHR1F10POLBCCR5 | |
| SCHEMBL784472 | 0.86 | CTSS (0.41) | MCHR1F10POLBROCK2DRD2 | |
| SCHEMBL785100 | 0.86 | KCNH2 (0.42) | MCHR1F10CCR5ROCK2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| CN-103097354-A | Substituted benzamide compounds | GRUENENTHAL CHEMIE | 2013-05-08 | — | — | CN | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | ACHE 746/4885MCHR1 363/4885F10 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.