Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785978 | 1.00 | TP53 (0.43) | TP53DRD3TRPM8SLC6A2SLC6A4 | |
| SCHEMBL803508 | 0.89 | WDR5 (0.41) | TP53TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL785382 | 0.89 | SLC6A2 (0.43) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL785381 | 0.89 | SLC6A2 (0.43) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL784639 | 0.88 | DRD3 (0.41) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL784638 | 0.88 | DRD3 (0.41) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL484953 | 0.87 | SLC6A2 (0.42) | TP53DRD3TRPM8SLC6A2SLC6A4 | |
| SCHEMBL786012 | 0.87 | SLC6A2 (0.43) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL784506 | 0.87 | TRPM8 (0.41) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL784944 | 0.87 | SLC6A2 (0.43) | DRD3TRPM8SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | TP53 4295/4885DRD3 85/4885TRPM8 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.