SCHEMBL785191

SCHEMBL785191

Cc1cc(O)c(C)c(C(C)(C)C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.43
CYP2C19 P33261 4/20 0.43
CYP1A2 P05177 3/20 0.43
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
ALOX15 P16050 4/20 0.39
CYP3A4 P08684 3/20 0.39
HIF1A Q16665 3/20 0.39
TP53 P04637 3/20 0.39
MAPK1 P28482 2/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
USP2 O75604 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
CA2 P00918 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9132733 0.84 SELL (0.40) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL396132 0.84 CYP2C9 (0.45) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL9844420 0.84 ALDH1A1 (0.41) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL784959 0.82 CYP2C9 (0.43) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL1882430 0.80 SMN1; SMN2 (0.52) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL31424079 0.80 CYP2C19 (0.52) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL1476812 0.80 CYP2C19 (0.52) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL14840362 0.79 ALDH1A1 (0.40) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL9339204 0.79 ALDH1A1 (0.41) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2
SCHEMBL30463035 0.78 ALDH1A1 (0.39) CYP2C9CYP2C19CYP1A2ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-20120071596-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2012-03-22 US disclosed
US-7601378-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-10-13 US disclosed
US-7595074-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-09-29 US disclosed
US-7507454-B2 Polymeric antioxidants UNIVERSITY OF MASSACHUSETTS LOWELL (US) 2009-03-24 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070154430-A1 Polymeric antioxidants MASSACHUSETTS LOWELL, UNIVERSITY OF 2007-07-05 US disclosed
US-20070154608-A1 Antioxidant preservatives to increase the shelf life and palatability of lipid-containing foods and other products containing moieties (e.g., unsaturated carbon-carbon bonds) that can be damaged by free radicals; hydroxy substituted benzene polymers UNIVERSITY OF MASSACHUSETTS LOWELL 2007-07-05 US disclosed
US-20070154720-A1 Polymeric antioxidants CHOLLI ASHOK L 2007-07-05 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-7223432-B2 Polymeric antioxidants University of Massachusettes Lowell (US) 2007-05-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070154430-A1 Polymeric antioxidants GPX4, NQO1, LPO CYP2C9 1968/4885CYP2C19 2488/4885CYP1A2 1877/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.