Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7855653 | 0.84 | POLB (0.36) | EGLN1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7854244 | 0.81 | MAPT (0.41) | KDM4ENPC1RAB9AGAAALDH1A1 | |
| SCHEMBL7854334 | 0.78 | PTGS1 (0.39) | KDM4EGAAEGLN1ALDH1A1POLB | |
| SCHEMBL7844774 | 0.77 | PTGS1 (0.38) | KDM4EGAAEGLN1ALDH1A1POLB | |
| SCHEMBL7856424 | 0.77 | ALDH1A1 (0.40) | KDM4ENPC1RAB9AGAAEGLN1 | |
| SCHEMBL7844769 | 0.76 | HDAC1 (0.37) | EGLN1ALDH1A1LMNAPOLBHTT | |
| SCHEMBL7854439 | 0.75 | KDM4E (0.33) | KDM4EGAAALDH1A1MAPTMEN1 | |
| SCHEMBL7845505 | 0.74 | KDM4E (0.32) | KDM4EGAAMAPT | |
| SCHEMBL7853643 | 0.74 | KDM4E (0.32) | KDM4EGAA | |
| SCHEMBL7852043 | 0.73 | MEN1 (0.35) | KDM4EGAAEGLN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084330-C | Cydic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-05-08 | — | — | CN | claimed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | claimed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | claimed |
| CN-1130377-A | Cyclic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-04 | — | — | CN | claimed |