SCHEMBL785263

SCHEMBL785263

CC(C)(C)c1cc(CCC(=O)OCc2ccc(O)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.52
KMT2A Q03164 5/20 0.49
ALDH1A1 P00352 2/20 0.45
HTT P42858 2/20 0.45
LMNA P02545 1/20 0.45
AGTR1 P30556 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 4/20 0.44
APP P05067 1/20 0.41
MET P08581 1/20 0.40
ALOX5 P09917 1/20 0.40
USP2 O75604 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
BLM P54132 1/20 0.40
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8526866 0.90 GAA (0.52) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL858494 0.85 GAA (0.60) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL208761 0.85 GAA (0.60) GAAKMT2AALDH1A1HTTLMNA
Ethane SCHEMBL9814026 0.84 GAA (0.59) GAAKMT2AALDH1A1HTTLMNA
Methane SCHEMBL5968168 0.84 GAA (0.59) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL429811 0.83 GAA (0.52) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL784927 0.83 ALDH1A1 (0.46) GAAKMT2AALDH1A1HTTLMNA
Ethylene SCHEMBL4038426 0.82 GAA (0.57) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL30209 0.82 GAA (0.57) GAAKMT2AALDH1A1HTTLMNA
SCHEMBL22604659 0.82 GAA (0.57) GAAKMT2AALDH1A1HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same POLNOX CORPORATION 2008-12-18 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007064843-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2007-06-07 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080311065-A1 Anti-oxidant macromonomers and polymers and methods of making and using the same GPX4, LPO, GPX1 GAA 2199/4885KMT2A 2526/4885ALDH1A1 167/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.