Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.44 |
| ▸ | JUN | P05412 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5091586 | 0.95 | FOS (0.46) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL5089195 | 0.89 | ALDH1A1 (0.48) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL7146465 | 0.88 | PDE4A (0.41) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL5092765 | 0.84 | FOS (0.47) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL27570893 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL5093430 | 0.80 | RAB9A (0.49) | SMN1; SMN2MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL5098932 | 0.79 | FOS (0.47) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL5089111 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2MAPTALDH1A1MAPK1LMNA | |
| SCHEMBL5089344 | 0.78 | MAPT (0.48) | FOSJUNNFKB1NFKB2RELA | |
| SCHEMBL5099951 | 0.77 | MAPT (0.47) | FOSJUNNFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |