Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | CES1 | P23141 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830415 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL693987 | 0.80 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| Hydrogen Sulfide SCHEMBL29028321 | 0.78 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL3731992 | 0.78 | LMNA (0.48) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL3383699 | 0.77 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL4021295 | 0.76 | LMNA (0.47) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL4662816 | 0.76 | LMNA (0.47) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL15834917 | 0.76 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL11798431 | 0.74 | MAPT (0.45) | SMN1; SMN2LMNAMAPTNPSR1XBP1 | |
| SCHEMBL8285027 | 0.74 | LMNA (0.45) | SMN1; SMN2LMNAMAPTNPSR1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |