SCHEMBL3731992

SCHEMBL3731992

C=C(c1ccccc1)C(C)O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
XBP1 P17861 1/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 3/20 0.40
PKM P14618 2/20 0.40
ADRA2C P18825 2/20 0.40
HPGD P15428 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CHRM2 P08172 1/20 0.40
ADRA1A P35348 1/20 0.40
RGS12 O14924 1/20 0.40
GLA P06280 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL693987 0.82 SMN1; SMN2 (0.50) LMNASMN1; SMN2MAPTNPSR1XBP1
Hydrogen Sulfide SCHEMBL29028321 0.80 SMN1; SMN2 (0.48) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL6533899 0.79 LMNA (0.41) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL7854232 0.78 SMN1; SMN2 (0.52) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL5381497 0.78 ALDH1A1 (0.42) LMNASMN1; SMN2NPSR1ATMALDH1A1
SCHEMBL830415 0.78 SMN1; SMN2 (0.47) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL4662816 0.78 LMNA (0.47) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL4021295 0.78 LMNA (0.47) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL11798431 0.76 MAPT (0.45) LMNASMN1; SMN2MAPTNPSR1XBP1
SCHEMBL2903960 0.76 MAOA (0.41) LMNAALDH1A1HPGDL3MBTL1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117844445-B Organic silicon liquid adhesive for LED and preparation method thereof 江苏诚睿达光电有限公司 2025-05-09 CN disclosed
CN-117844445-A Organic silicon liquid adhesive for LED and preparation method thereof 江苏诚睿达光电有限公司 2024-04-09 CN disclosed
EP-1637550-B1 Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby UNIV CARNEGIE MELLON (US) 2017-09-20 EP disclosed
US-20120172392-A1 AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES SALTER-CID LUISA M (US) 2012-07-05 US disclosed
US-20120172392-A1 AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES SALTER-CID LUISA M (US) 2012-07-05 US disclosed
EP-2283833-A2 Amines and amides for the treatment of diseases LA JOLLA PHARMACEUTICAL CO. (US) 2011-02-16 EP disclosed
US-7825199-B1 mediated by transition metal complex in redox reaction of atom transfer Atom Transfer Coupling Reaction to/from initiator or dormant polymer and growing active polymer chain ends; transition metal held in close conjunction with a solid support; salt containing a soluble organic counterion; styrene graft CARNEGIE MELLON UNIVERSITY (US) 2010-11-02 US disclosed
US-20070078157-A1 Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO)enzyme activity and VAP-1 mediated adhesion useful for treatment of diseases LA JOLLA PHARMACEUTICAL COMPANY (US) 2007-04-05 US disclosed
US-20070078157-A1 Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO)enzyme activity and VAP-1 mediated adhesion useful for treatment of diseases LA JOLLA PHARMACEUTICAL COMPANY (US) 2007-04-05 US disclosed
EP-1637550-A2 Catalytic processes for the controlled polymerization of free radically (co) polymerizable monomers and functional polymeric systems prepared thereby CARNEGIE-MELLON UNIVERSITY (US) 2006-03-22 EP disclosed
EP-1171496-B1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY UNIV CARNEGIE MELLON (US) 2005-12-07 EP disclosed
US-20040171779-A1 Redox systems; using transition metal complex catalysts; atom transfer radical polymerization CARNEGIE MELLON UNIVERSITY (A NON-PROFIT PENNSYLVANIA ORGANIZATION) 2004-09-02 US disclosed
EP-0945420-B1 Process for the preparation of bisphenols MITSUI CHEMICALS INC (JP) 2002-06-12 EP disclosed
EP-1171496-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE-MELLON UNIVERSITY (US) 2002-01-16 EP disclosed
US-6316677-B1 REACTING PHENOLIC COMPOUND WITH DIALKYLBENZENE, BIS(HYDROXYALKYL)BENZENE, OR (HYDROXYALKYL)-ALKENYLBENZENE; NEUTRALIZATION USING ANION EXCHANGE RESIN; CONCENTRATION, ISOLATION MITSUI CHEMICALS, INC. (JP) 2001-11-13 US disclosed
EP-0719258-B1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMA CO LTD (JP) 2001-10-31 EP disclosed
WO-2000056795-A1 CATALYTIC PROCESSES FOR THE CONTROLLED POLYMERIZATION OF FREE RADICALLY (CO)POLYMERIZABLE MONOMERS AND FUNCTIONAL POLYMERIC SYSTEMS PREPARED THEREBY CARNEGIE MELLON UNIVERSITY (US) 2000-09-28 WO disclosed
EP-0945420-A1 Process for the preparation of bisphenols Mitsui Chemicals, Inc. (JP) 1999-09-29 EP disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070078157-A1 Amine-based and amide-based inhibitors of semicarbazide-sensitive amine oxidase (SSAO)enzyme activity and VAP-1 mediated adhesion useful for treatment of diseases VCAM1, AOC2, AOC1 LMNA 4198/4885SMN1; SMN2 1636/4885MAPT 1330/4885
US-20120172392-A1 AMINE-BASED AND AMIDE-BASED INHIBITORS OF SEMICARBAZIDE-SENSITIVE AMINE OXIDASE (SSAO) ENZYME ACTIVITY AND VAP-1 MEDIATED ADHESION USEFUL FOR TREATMENT OF DISEASES VCAM1, AOC2, AOC1 LMNA 4198/4885SMN1; SMN2 1636/4885MAPT 1330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.