Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP8 | P40818 | 3/20 | 0.37 |
| ▸ | USP7 | Q93009 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | BCL2 | P10415 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187098 | 0.73 | MEN1 (0.55) | USP8USP7SMN1; SMN2USP47ALDH1A1 | |
| SCHEMBL29496222 | 0.73 | MEN1 (0.55) | USP8USP7SMN1; SMN2USP47ALDH1A1 | |
| SCHEMBL8144473 | 0.72 | TDP2 (0.50) | SMN1; SMN2ALDH1A1BCL2CDC25BNPC1 | |
| SCHEMBL3625568 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1CDC25BNPC1LMNA | |
| SCHEMBL28383679 | 0.69 | USP8 (0.50) | USP8USP7SMN1; SMN2USP47BCL2 | |
| SCHEMBL10696799 | 0.68 | RAB9A (0.39) | USP8USP7SMN1; SMN2USP47ALDH1A1 | |
| SCHEMBL526269 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1BCL2CDC25BNPC1 | |
| SCHEMBL29808347 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1BCL2CDC25BNPC1 | |
| SCHEMBL11443355 | 0.67 | ESR2 (0.38) | USP8USP7SMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL395873 | 0.67 | LMNA (0.47) | USP8USP7SMN1; SMN2USP47ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144407-A1 | CYCLIC GUANIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | Bayer Aktiengesellschaft (DE) | 2001-10-17 | — | — | EP | disclosed |
| EP-1023276-A1 | MICROBICIDE 1,4,2-DIOXACINE DERIVATIVES | BAYER AG (DE) | 2000-08-02 | — | — | EP | disclosed |
| WO-2000040582-A1 | CYCLIC GUANIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-07-13 | — | — | WO | disclosed |
| WO-1999019312-A1 | MICROBICIDE 1,4,2-DIOXACINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-04-22 | — | — | WO | disclosed |