Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.34 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Asparagine SCHEMBL2927424 | 0.95 | SLC1A3 (0.32) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| Asparagine SCHEMBL2902140 | 0.83 | — | — | |
| Asparagine SCHEMBL2902050 | 0.73 | SLC1A3 (0.34) | SLC1A3SLC1A2SLC1A1TPH1 | |
| SCHEMBL2906893 | 0.72 | CTSB (0.39) | — | |
| Asparagine SCHEMBL7855451 | 0.69 | MC4R (0.36) | SLC6A4SLC6A3 | |
| Asparagine SCHEMBL28219869 | 0.64 | SLC7A5 (0.52) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| Dl-Phenylalanine SCHEMBL28019412 | 0.61 | SLC7A5 (0.69) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| Asparagine SCHEMBL7325420 | 0.61 | SLC7A5 (0.56) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| Asparagine SCHEMBL14486114 | 0.61 | SLC7A5 (0.56) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 | |
| Asparagine SCHEMBL14486115 | 0.61 | SLC7A5 (0.56) | SLC1A3SLC1A2SLC1A1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157040-A1 | LOW MOLECULAR WEIGHT PEPTIDE DERIVATIVES AS INHIBITORS OF THE LAMININ/NIDOGEN INTERACTION | Aventis Pharma Deutschland GmbH (DE) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000052051-A1 | LOW MOLECULAR WEIGHT PEPTIDE DERIVATIVES AS INHIBITORS OF THE LAMININ/NIDOGEN INTERACTION | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-09-08 | — | — | WO | disclosed |