Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7022814 | 0.89 | MAPT (0.39) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7256594 | 0.84 | GSK3B (0.50) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7022502 | 0.84 | MEN1 (0.43) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL4970607 | 0.82 | GSK3B (0.55) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7852739 | 0.82 | GSK3B (0.38) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7850973 | 0.82 | GSK3B (0.40) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7853884 | 0.79 | SMN1; SMN2 (0.35) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7022685 | 0.79 | HTR7 (0.42) | MAPTSMN1; SMN2POLBALDH1A1GSK3B | |
| SCHEMBL7853388 | 0.76 | GSK3B (0.49) | MAPTSMN1; SMN2POLBRAB9ANPC1 | |
| SCHEMBL7255038 | 0.76 | GSK3B (0.49) | MAPTSMN1; SMN2POLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087963-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | Chiron Corporation (US) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065897-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |