Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654281 | 0.84 | HIF1A (0.45) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7659448 | 0.84 | TP53 (0.37) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7657396 | 0.84 | PTPN2 (0.41) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7665046 | 0.84 | HIF1A (0.42) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7858188 | 0.83 | TDP1 (0.45) | TP53MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7659818 | 0.83 | PKM (0.36) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7656711 | 0.82 | HIF1A (0.44) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7658172 | 0.82 | HIF1A (0.44) | TP53MAPTMEN1KMT2ATHRB | |
| SCHEMBL7660123 | 0.81 | HSPD1 (0.47) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7658431 | 0.79 | LMNA (0.53) | HTR6TP53MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1109800-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LIMITED (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000012496-A1 | NOVEL CDK INHIBITORS HAVING FLAVONE STRUCTURE | LG CHEMICAL LTD. (KR) | 2000-03-09 | — | — | WO | disclosed |