Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | FCER2 | P06734 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.43 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.43 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.43 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.43 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.43 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.43 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.43 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857944 | 0.84 | MMP9 (0.45) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL1245446 | 0.83 | BDKRB2 (0.46) | TRPV1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL1244207 | 0.83 | SCN9A (0.51) | MMP2HDAC1HDAC4HDAC3HDAC7 | |
| SCHEMBL7860797 | 0.83 | MMP9 (0.46) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL1244196 | 0.81 | BDKRB2 (0.48) | MMP9MMP2MMP8TRPV1ADCY6 | |
| SCHEMBL13365364 | 0.81 | HDAC1 (0.46) | TRPV1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL1244301 | 0.80 | BDKRB2 (0.47) | MMP9MMP2MMP8TRPV1HDAC1 | |
| SCHEMBL7857825 | 0.80 | CALCRL (0.46) | MMP9MMP2MMP8CALCRL | |
| SCHEMBL12890816 | 0.80 | BDKRB2 (0.47) | MMP9MMP2MMP8TRPV1HDAC1 | |
| SCHEMBL7860837 | 0.80 | MMP8 (0.44) | MMP9MMP1FCER2MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |