Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.38 |
| ▸ | CHRNG | P07510 | 3/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.38 |
| ▸ | CHRND | Q07001 | 3/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7857825 | 0.87 | CALCRL (0.46) | MMP9MMP2MMP8CHRNB2CHRNB4 | |
| SCHEMBL7860837 | 0.86 | MMP8 (0.44) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL7857107 | 0.84 | MMP9 (0.46) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL7857101 | 0.84 | MMP9 (0.45) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL7860797 | 0.84 | MMP9 (0.46) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL8162601 | 0.84 | MMP2 (0.50) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL7857911 | 0.82 | MMP2 (0.44) | MMP9FCER2MMP2MMP8 | |
| Trifluoroacetic Acid SCHEMBL7857833 | 0.81 | MMP2 (0.46) | MMP9MMP1FCER2MMP3MMP2 | |
| SCHEMBL1244207 | 0.77 | SCN9A (0.51) | MMP2HDAC4HDAC1 | |
| SCHEMBL7857954 | 0.75 | MMP2 (0.43) | MMP9MMP2MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |