SCHEMBL7857405

SCHEMBL7857405

[Li]c1ccccc1CC(CO)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 4/20 0.35
GABBR2 O75899 2/20 0.34
GABBR1 Q9UBS5 2/20 0.34
CYP2D6 P10635 2/20 0.33
CYP1A2 P05177 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
KMT2A Q03164 1/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
KCNH2 Q12809 2/20 0.32
KCNA5 P22460 2/20 0.32
GSR P00390 1/20 0.32
LMNA P02545 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
PSMB5 P28074 3/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11860261 0.78 SLC6A2 (0.45) CYP2D6CYP1A2PKMKMT2ALMNA
SCHEMBL7263509 0.75 FOLH1 (0.48) GABBR2GABBR1CYP2D6CYP1A2PKM
SCHEMBL148756 0.75 TRPA1 (0.48) TRPA1GABBR2GABBR1CYP2D6CYP1A2
SCHEMBL7683619 0.74 MTNR1A (0.42) TRPA1MTNR1AMTNR1BSLC6A2SLC6A4
SCHEMBL597894 0.74 MTNR1A (0.53) TRPA1CYP1A2MTNR1AMTNR1BSLC6A2
SCHEMBL9802284 0.74 L3MBTL1 (0.51) CYP2D6CYP1A2SMN1; SMN2KMT2AKCNH2
Boric Acid SCHEMBL21356833 0.73 TRPA1 (0.43) TRPA1GABBR2GABBR1CYP2D6CYP1A2
SCHEMBL3878722 0.71 ALDH1A1 (0.53) KMT2AGSRL3MBTL1
SCHEMBL28884491 0.71 TRPA1 (0.50) TRPA1GABBR2GABBR1CYP2D6CYP1A2
SCHEMBL11853217 0.69 MEN1 (0.41) CYP2D6CYP1A2KMT2ALMNASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001000631-A1 NEW CLASSES OF HIGH LINEAR AND NONLINEAR RESPONSE COMPOUNDS NANOWORKS, INC. (US) 2001-01-04 WO disclosed