Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803284 | 1.00 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL803734 | 0.90 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3ACHEDRD2 | |
| SCHEMBL785540 | 0.87 | TRPM8 (0.40) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL803262 | 0.87 | TRPM8 (0.40) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL785598 | 0.86 | RORC (0.41) | DRD3 | |
| SCHEMBL785597 | 0.86 | RORC (0.41) | DRD3 | |
| SCHEMBL785167 | 0.86 | TP53 (0.43) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL785978 | 0.86 | TP53 (0.43) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL784735 | 0.84 | TRPM8 (0.42) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 | |
| SCHEMBL803606 | 0.84 | TRPM8 (0.42) | SLC6A2SLC6A4SLC6A3DRD3TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | SLC6A2 1966/4885SLC6A4 1682/4885SLC6A3 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.